Background

• N-Acetylcysteine (NAC) is an amino acid derivative that exhibits psychiatric effects through the modulation of glutamate neurotransmission and its antioxidant properties.
• NAC has shown promise in many psychiatric illnesses, including schizophrenia, bipolar disorder, obsessive-compulsive disorder (OCD), addiction, nail biting, and skin picking.
• Some evidence suggests treatment with NAC in autistic patients is beneficial for aggression, irritability, and self-injurious behaviors.

The purpose of this study was to determine if NAC has effects on aggression, self-injurious behaviors, inappropriate sexual behaviors, and group attendance in the non-autistic patient population.

To determine if the addition of NAC to a patient’s medication regimen changes:

• Incidence of verbal and physical aggression
• Incidence of self-injurious behavior
• Incidence of inappropriate sexual behaviors
• Group attendance
  

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